SCHEMBL19485490

SCHEMBL19485490

CCc1ncc(Br)c(Cl)n1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7830803 0.79 POLB (0.36) KMT2APOLBGAA
SCHEMBL16435594 0.79 POLB (0.36) KMT2APOLBGAA
SCHEMBL18399105 0.78 TDP1 (0.33) KMT2AMEN1
SCHEMBL12514788 0.78
SCHEMBL19336271 0.77 MBOAT4 (0.31) KMT2A
SCHEMBL22114663 0.77 RPS6KA5 (0.34)
SCHEMBL25543278 0.75 APLNR (0.32)
SCHEMBL28128731 0.75 NOS3 (0.31) KMT2A
SCHEMBL10271518 0.72 GAA (0.37) GAA
SCHEMBL12963737 0.72 MBOAT4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9795613-B2 GLP-1 receptor modulators CELGENE INTERNATIONAL II SÀRL (CH) 2017-10-24 US disclosed