Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26301903 | 0.81 | KDM4E (0.33) | MBOAT4NPC1RAB9AKMT2A | |
| SCHEMBL12514788 | 0.80 | — | — | |
| SCHEMBL3055813 | 0.79 | ALDH1A1 (0.39) | — | |
| SCHEMBL19743756 | 0.78 | MBOAT4 (0.32) | MBOAT4 | |
| SCHEMBL19485490 | 0.77 | KMT2A (0.36) | KMT2A | |
| SCHEMBL22282975 | 0.75 | HSD11B1 (0.36) | NPC1RAB9A | |
| SCHEMBL28267941 | 0.74 | UHRF1 (0.35) | — | |
| SCHEMBL2115976 | 0.74 | LMNA (0.33) | — | |
| SCHEMBL12344269 | 0.74 | RXRA (0.37) | — | |
| SCHEMBL28759514 | 0.74 | SMN1; SMN2 (0.43) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3216792-A1 | LACTAM KINASE INHIBITORS | Tavares, Francis Xavier (US) | 2017-09-13 | — | — | EP | disclosed |