Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.40 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.39 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | S100B | P04271 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19486301 | 0.92 | LTA4H (0.40) | LTA4HPRSS1TMPRSS2MEN1MAPT | |
| SCHEMBL19481636 | 0.82 | PRSS1 (0.33) | PRSS1TMPRSS2PRMT1F2ST14 | |
| SCHEMBL18883788 | 0.80 | MAOB (0.45) | LTA4HNR5A1GAARAB9AMEN1 | |
| SCHEMBL19486307 | 0.75 | F2 (0.49) | LTA4HNR5A1PRSS1TMPRSS2F2 | |
| SCHEMBL15149435 | 0.73 | PRSS1 (0.47) | PRSS1TMPRSS2PRMT1F2ST14 | |
| SCHEMBL16360536 | 0.73 | LMNA (0.33) | — | |
| SCHEMBL13541415 | 0.70 | LTA4H (0.50) | LTA4HNR5A1CYP2D6GAARAB9A | |
| SCHEMBL18735816 | 0.70 | NOS1 (0.42) | PRSS1F2PLAUF10PLG | |
| SCHEMBL31628187 | 0.70 | NOS1 (0.42) | PRSS1F2PLAUF10PLG | |
| SCHEMBL27291557 | 0.70 | RAB9A (0.52) | CYP2D6GAARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180148439-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N-SULFATED BETA LACTAMS | ARIXA PHARMACEUTICALS, INC. | 2018-05-31 | — | — | US | disclosed |
| US-20170298057-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N- SULFATED BETA LACTAMS | ARIXA PHARMACEUTICALS, INC. | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298057-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N- SULFATED BETA LACTAMS | DDOST, LBR, STS | LTA4H 1637/4885NR5A1 815/4885PRSS1 295/4885 |
| US-20180148439-A1 | DEUTERATED O-SULFATED BETA LACTAM HYDROXAMIC ACIDS AND DEUTERATED N-SULFATED BETA LACTAMS | DDOST, LBR, STS | LTA4H 1637/4885NR5A1 815/4885PRSS1 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.