Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 14/20 | 0.62 |
| ▸ | NOS3 | P29474 | 11/20 | 0.62 |
| ▸ | NOS1 | P29475 | 11/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19241056 | 0.84 | NOS3 (0.59) | NOS2NOS3NOS1 | |
| SCHEMBL19240920 | 0.79 | NOS2 (0.64) | NOS2NOS3NOS1 | |
| SCHEMBL12093365 | 0.79 | NOS3 (0.41) | NOS2NOS3NOS1 | |
| SCHEMBL7049604 | 0.77 | NOS2 (1.00) | NOS2NOS3NOS1 | |
| SCHEMBL15259149 | 0.77 | NOS2 (0.69) | NOS2NOS3NOS1 | |
| SCHEMBL5673354 | 0.75 | NOS2 (0.67) | NOS2NOS3NOS1 | |
| SCHEMBL13040600 | 0.74 | NOS2 (0.69) | NOS2NOS3NOS1 | |
| SCHEMBL17721458 | 0.73 | NOS2 (0.79) | NOS2NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL5674986 | 0.73 | NOS2 (0.64) | NOS2NOS3NOS1 | |
| SCHEMBL6279267 | 0.73 | NOS2 (0.71) | NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167260-B2 | 2-aminopyridine-based selective neuronal nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2019-01-01 | — | — | US | disclosed |
| US-20170298021-A1 | 2-Aminopyridine-based Selective Neuronal Nitric Oxide Synthase Inhibitors | NORTHWESTERN UNIVERSITY (US) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167260-B2 | 2-aminopyridine-based selective neuronal nitric oxide synthase inhibitors | NOS2, NOS1, NOS3 | NOS2 1/4885NOS3 3/4885NOS1 2/4885 |
| US-20170298021-A1 | 2-Aminopyridine-based Selective Neuronal Nitric Oxide Synthase Inhibitors | NOS2, NOS1, NOS3 | NOS2 1/4885NOS3 3/4885NOS1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.