Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 5/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19459466 | 0.90 | KMO (0.39) | PIK3C3AXLALPLOXTRAVPR1A | |
| SCHEMBL20647665 | 0.89 | ALPL (0.40) | PIK3C3AXLALPLOXTRAVPR1A | |
| SCHEMBL19483205 | 0.84 | KMO (0.39) | PIK3C3ALPLOXTRAVPR1AGPBAR1 | |
| SCHEMBL25962937 | 0.76 | ALPL (0.41) | ALPLOXTRAVPR1AGPBAR1CTSA | |
| SCHEMBL17671206 | 0.76 | CSF1R (0.37) | AXLALPLCTSAKMOSCN9A | |
| SCHEMBL17671183 | 0.75 | AXL (0.41) | PIK3C3AXLALPLCTSASCN9A | |
| SCHEMBL17671207 | 0.73 | NPC1 (0.39) | PIK3C3AXLALPLCTSASCN9A | |
| SCHEMBL19459553 | 0.72 | HSPB1 (0.48) | — | |
| SCHEMBL22345002 | 0.66 | DPP4 (0.36) | AXLALPLKMOMAPK14 | |
| SCHEMBL17671204 | 0.65 | CES2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298008-A1 | TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298008-A1 | TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION | AHR, ARSA, ALK | PIK3C3 2512/4885AXL 1107/4885ALPL 4194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.