SCHEMBL194888

SCHEMBL194888

CN(C)c1ccc(C(=O)C(=O)c2ccc(N(C)C)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.83
ALDH1A1 P00352 6/20 0.73
MAPT P10636 5/20 0.73
HPGD P15428 3/20 0.73
NPC1 O15118 5/20 0.61
ALOX15 P16050 2/20 0.58
TSHR P16473 2/20 0.58
HSD17B10 Q99714 1/20 0.58
MAPK1 P28482 2/20 0.56
CYP3A4 P08684 1/20 0.56
HBB P68871 1/20 0.56
KMT2A Q03164 6/20 0.55
MEN1 O00255 4/20 0.55
HDAC1 Q13547 3/20 0.55
HDAC6 Q9UBN7 3/20 0.55
POLB P06746 2/20 0.55
KDM4E B2RXH2 2/20 0.55
TDP1 Q9NUW8 1/20 0.53
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4140401 0.91 RAB9A (1.00) RAB9AALDH1A1MAPTHPGDNPC1
SCHEMBL11711659 0.89 RAB9A (0.68) RAB9AALDH1A1MAPTHPGDNPC1
SCHEMBL10840719 0.89 ALDH1A1 (0.70) RAB9AALDH1A1MAPTHPGDNPC1
SCHEMBL8693345 0.89 RAB9A (0.68) RAB9AALDH1A1MAPTHPGDNPC1
SCHEMBL30671562 0.89 RAB9A (0.96) RAB9AALDH1A1MAPTHPGDNPC1
SCHEMBL4174554 0.88 RAB9A (0.73) RAB9AALDH1A1MAPTHPGDNPC1
SCHEMBL9187568 0.88 RAB9A (0.67) RAB9AALDH1A1MAPTHPGDNPC1
SCHEMBL3829871 0.85 RAB9A (0.63) RAB9AALDH1A1MAPTHPGDNPC1
SCHEMBL8695963 0.85 RAB9A (0.63) RAB9AALDH1A1MAPTHPGDNPC1
Michler'S Ketone SCHEMBL10883748 0.85 RAB9A (0.89) RAB9AALDH1A1MAPTHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7973034-B2 Ameliorating toxic effects of such as cancer therapy drugs or addictive drug overdose ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) 2011-07-05 US claimed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
US-6635090-B1 Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL, S.A. (FR) 2003-10-21 US claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
EP-4743828-A1 PHOTOCURABLE AS WELL AS THERMALLY CURABLE COMPOSITIONS SUITABLE FOR LOW TEMPERATURE CURING BASF SE (DE) 2026-05-20 EP disclosed
WO-2025011754-A1 PHOTOCURABLE AS WELL AS THERMALLY CURABLE COMPOSITIONS SUITABLE FOR LOW TEMPERATURE CURING BASF SE (DE) 2025-01-16 WO disclosed
EP-4114825-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2024-11-20 EP disclosed
WO-2024181097-A1 PHOTOCURABLE COMPOSITION, METHOD FOR PRODUCING CURED ARTICLE, FILM, OPTICAL ELEMENT, IMAGE SENSOR, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, AND RADICAL POLYMERIZATION INITIATOR 富士フイルム株式会社 2024-09-06 WO disclosed
CN-113583321-B Crosslinkable polyethylene composition, preparation method and application thereof, crosslinked polyethylene and application thereof 国家能源投资集团有限责任公司 2024-07-23 CN disclosed
CN-113621187-B Crosslinkable insulating polyolefin composition, preparation method and application thereof, crosslinked insulating polyolefin and application thereof 国家能源投资集团有限责任公司 2024-05-07 CN disclosed
US-4721734-A PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-01-26 US disclosed
US-4576975-A Water soluble Michler's ketone analogs in combined photoinitiator composition and polymerizable composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-03-18 US disclosed
EP-0167973-A1 Redox indicators Roche Diagnostics GmbH (DE) 1986-01-15 EP disclosed
EP-0166230-A1 2,3-Bis(dialkylaminophenyl)quinoxalines and their use in electrographic recording materials HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-02 EP disclosed
EP-0165588-A2 Analytical reagent, analytical method, and multilayer chemical-analytical element FUJI PHOTO FILM CO., LTD. (JP) 1985-12-27 EP disclosed
US-4507497-A PHOTOPOLYMERIZATION INITIATOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-03-26 US disclosed
US-4347111-A PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS, HARDENING OF PRINTING DYES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 RAB9A 4652/4885ALDH1A1 83/4885MAPT 685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.