SCHEMBL194889

SCHEMBL194889

C[CH]OC(=O)c1ccccc1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.62
TSHR P16473 2/20 0.62
HPGD P15428 8/20 0.53
HSD17B10 Q99714 4/20 0.53
ALOX15 P16050 2/20 0.53
TDP1 Q9NUW8 2/20 0.52
ALDH1A1 P00352 6/20 0.49
KDM4E B2RXH2 6/20 0.49
SMN1; SMN2 Q16637 3/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
HMGB1 P09429 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
CA14 Q9ULX7 1/20 0.48
MAPT P10636 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3366780 0.85 LMNA (0.58) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL9615190 0.83 LMNA (0.56) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL7215099 0.82 TSHR (0.59) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL6890686 0.80 NPC1 (0.47) LMNATSHRHPGDMAPTHTT
SCHEMBL194863 0.80 TSHR (0.57) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL27817064 0.80 HPGD (0.58) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL28543902 0.78 LMNA (0.60) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL9565921 0.78 ALDH1A1 (0.63) TSHRHPGDHSD17B10TDP1ALDH1A1
SCHEMBL6886783 0.77 HPGD (0.53) TSHRHPGDHSD17B10ALDH1A1SMN1; SMN2
Methyl Salicylate SCHEMBL29370254 0.77 LMNA (1.00) LMNATSHRHPGDHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 US disclosed
EP-3019473-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2020-02-19 EP disclosed
US-10488756-B2 Oxime ester photoinitiators BASF SE (DE) 2019-11-26 US disclosed
EP-3354641-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-07-17 EP disclosed
US-10234761-B2 Oxime ester photoinitiators BASF SE (DE) 2019-03-19 US disclosed
EP-2847167-B9 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-02-20 EP disclosed
EP-3354641-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2018-08-01 EP disclosed
EP-2847167-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2018-07-18 EP disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed
EP-1410109-A1 PHOTOSENSITIVE RESIN COMPOSITION Ciba SC Holding AG (CH) 2004-04-21 EP disclosed
EP-1395615-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE Ciba SC Holding AG (CH) 2004-03-10 EP disclosed
US-6596445-B1 Initiators for photopolymerization of radically polymerizable compounds CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-22 US disclosed
WO-2003010602-A1 PHOTOSENSITIVE RESIN COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-02-06 WO disclosed
WO-2002100903-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-12-19 WO disclosed
US-20020020832-A1 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORP. 2002-02-21 US disclosed
US-20010012596-A1 For resist applications; thermostability, storage stability CIBA SPECIALTY CHEMICALS CORP. 2001-08-09 US disclosed
US-5663212-A Light-sensitive resin composition FUJI PHOTO FILM CO., LTD. (JP) 1997-09-02 US disclosed
US-4007158-A 9-AZA- 1,5-DIOXA-SPIRO (5,5) UNDECANES SANKYO COMPANY LIMITED (JA) 1977-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 LMNA 2575/4885TSHR 528/4885HPGD 645/4885
US-10488756-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 LMNA 2575/4885TSHR 528/4885HPGD 645/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 LMNA 2745/4885TSHR 519/4885HPGD 641/4885
US-10234761-B2 Oxime ester photoinitiators C9, C5, CBR3 LMNA 1297/4885TSHR 333/4885HPGD 627/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 LMNA 2575/4885TSHR 528/4885HPGD 645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.