SCHEMBL3366780

SCHEMBL3366780

CC=COC(=O)c1ccccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
TSHR P16473 2/20 0.58
HPGD P15428 7/20 0.50
HSD17B10 Q99714 4/20 0.50
ALOX15 P16050 2/20 0.50
TDP1 Q9NUW8 2/20 0.49
ALDH1A1 P00352 6/20 0.46
KDM4E B2RXH2 5/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
HMGB1 P09429 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
CA14 Q9ULX7 1/20 0.45
MAPT P10636 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9615190 0.98 LMNA (0.56) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL28041527 0.88 TSHR (0.47) LMNATSHRHSD17B10ALOX15TDP1
SCHEMBL194889 0.85 LMNA (0.62) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL28740024 0.81 NPC1 (0.45) LMNATSHRHPGDMAPTHTT
SCHEMBL27412731 0.81 ALDH1A1 (0.52) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL28740020 0.80 CES2 (0.48) ALOX15TDP1ALDH1A1SMN1; SMN2MAPT
SCHEMBL28740015 0.80 CES2 (0.48) LMNATSHRHPGDALDH1A1KDM4E
SCHEMBL2974837 0.79 KDM4E (0.39) LMNATSHRHPGDHSD17B10TDP1
SCHEMBL11824051 0.79 MAPT (0.57) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL11824054 0.79 MAPT (0.57) LMNATSHRHPGDHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0147044-B1 BENZOFURANCARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM ADRIA LABORATORIES INC. (US) 1990-04-25 EP claimed
CN-106518647-A synthesis method of alkyl salicylic acid 中国石油天然气股份有限公司 2017-03-22 CN disclosed
CN-104487557-B Lubricating oil composition for continuously variable transmission 吉坤日矿日石能源株式会社 2016-08-17 CN disclosed
US-8415283-B2 Lubricating oil composition for diesel engine NIPPON OIL CORPORATION (JP) 2013-04-09 US disclosed
US-20100147238-A1 LUBRICATING OIL COMPOSITION FOR DIESEL ENGINE NIPPON OIL CORPORATION (JP) 2010-06-17 US disclosed
US-7629302-B2 Lubricating oil additive and lubricating oil composition NIPPON OIL CORPORATION (JP) 2009-12-08 US disclosed
CN-100558868-C Lubricating oil composition NIPPON OIL CORP (JP) 2009-11-11 CN disclosed
CN-100500818-C Lubricating oil compositions NIPPON OIL CORP (JP) 2009-06-17 CN disclosed
CN-100462424-C Lubricating oil compositions NIPPON OIL CORP (JP) 2009-02-18 CN disclosed
CN-100344740-C Lubricating oil composition NIPPON OIL CORP (JP) 2007-10-24 CN disclosed
US-20070179070-A1 Lubricating oil composition for diesel engine NIPPON OIL CORPORATION (JP) 2007-08-02 US disclosed
CN-1926225-A Lubricating oil composition NIPPON OIL CORP (JP) 2007-03-07 CN disclosed
EP-1736529-A1 LUBRICATING OIL COMPOSITION FOR DIESEL ENGINE Nippon Oil Corporation (JP) 2006-12-27 EP disclosed
US-20060063686-A1 Lubricating oil additive and lubricating oil composition NIPPON OIL CORPORATION (JP) 2006-03-23 US disclosed
CN-1681909-A Lubricating oil composition NIPPON OIL CORP (JP) 2005-10-12 CN disclosed
CN-1681910-A Lubricating oil compositions NIPPON OIL CORP (JP) 2005-10-12 CN disclosed
EP-1580257-A1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2005-09-28 EP disclosed
CN-1675342-A Lubricating oil composition NIPPON OIL CORP (JP) 2005-09-28 CN disclosed