Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | PDE8B | O95263 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19489656 | 0.89 | P2RY12 (0.35) | P2RY12 | |
| SCHEMBL19489654 | 0.80 | SLC6A3 (0.37) | P2RY12SLC6A3 | |
| SCHEMBL19490038 | 0.77 | ALDH1A1 (0.34) | ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL19489655 | 0.77 | P2RY12 (0.31) | P2RY12 | |
| SCHEMBL19489653 | 0.77 | P2RY12 (0.31) | P2RY12 | |
| SCHEMBL19489658 | 0.72 | KMT5B (0.31) | — | |
| SCHEMBL19490036 | 0.71 | ALDH1A1 (0.35) | ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL23316958 | 0.70 | — | — | |
| SCHEMBL19489648 | 0.69 | RXRA (0.38) | P2RY12SLC6A3PDE8BALDH1A1LMNA | |
| SCHEMBL20715116 | 0.67 | P2RY12 (0.32) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442945-B1 | TETRAHYDROISOQUINOLINE DERIVATIVES | UCB Biopharma SRL (BE) | 2020-07-08 | — | — | EP | disclosed |
| WO-2017178377-A1 | TETRAHYDROISOQUINOLINE DERIVATIVES | UCB BIOPHARMA SPRL (BE) | 2017-10-19 | — | — | WO | disclosed |