Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | GPR3 | P46089 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17177894 | 0.84 | POLB (0.50) | POLBGPR3CYP2D6HTR2ACYP3A4 | |
| SCHEMBL30713690 | 0.82 | CYP1A2 (0.49) | POLBGPR3CYP2D6HTR2ACYP3A4 | |
| SCHEMBL10518378 | 0.79 | GPR3 (0.46) | POLBGPR3CYP2D6HTR2ACYP3A4 | |
| SCHEMBL24603351 | 0.76 | S1PR1 (0.38) | POLBCYP2D6HTR2A | |
| SCHEMBL20920761 | 0.74 | POLB (0.48) | POLBGPR3CYP2D6HTR2AACHE | |
| SCHEMBL16866691 | 0.73 | HTR2A (0.47) | CYP2D6HTR2ACYP3A4HIF1A | |
| SCHEMBL10079529 | 0.72 | MAPT (0.48) | POLBCYP2D6CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL20999088 | 0.72 | PDE4B (0.39) | ACHEALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL18386009 | 0.72 | GPR3 (0.40) | POLBGPR3CYP2D6HTR2ACYP3A4 | |
| SCHEMBL20795338 | 0.69 | ALDH1A1 (0.36) | CYP2D6CYP3A4CYP2C19CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044327-A1 | DHNT MONOMERS AND POLYMER DYES WITH MODIFIED PHOTOPHYSICAL PROPERTIES | BECKMAN COULTER, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| US-20230399565-A1 | POLYMER DYES AND USES THEREOF | BECKMAN COULTER, INC. | 2023-12-14 | — | — | US | disclosed |
| US-11208527-B2 | Photoactive macromolecules and uses thereof | BECKMAN COULTER, INC. (US) | 2021-12-28 | — | — | US | disclosed |
| EP-3443049-B1 | PHOTOACTIVE MACROMOLECULES AND USES THEREOF | BECKMAN COULTER INC (US) | 2021-04-14 | — | — | EP | disclosed |
| US-20190144601-A1 | PHOTOACTIVE MACROMOLECULES AND USES THEREOF | BECKMAN COULTER, INC. | 2019-05-16 | — | — | US | disclosed |
| WO-2017180998-A2 | PHOTOACTIVE MACROMOLECULES AND USES THEREOF | BECKMAN COULTER, INC. (US) | 2017-10-19 | — | — | WO | disclosed |