Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | S100A4 | P26447 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CDC25B | P30305 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CDC25A | P30304 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939357 | 0.80 | MAPT (0.48) | MAPTTP53RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11547901 | 0.75 | EDNRA (0.43) | MAPTTP53RAB9ASMN1; SMN2HPGD | |
| SCHEMBL1699526 | 0.75 | ACHE (0.58) | LMNA | |
| SCHEMBL333528 | 0.74 | ELANE (0.36) | — | |
| SCHEMBL7317169 | 0.73 | TP53 (0.40) | MAPTTP53RAB9ASMN1; SMN2HPGD | |
| SCHEMBL19489752 | 0.72 | POLB (0.54) | MAPTTP53RAB9ASMN1; SMN2HPGD | |
| SCHEMBL677629 | 0.70 | MEN1 (0.55) | MAPTTP53RAB9ASMN1; SMN2HPGD | |
| SCHEMBL15245116 | 0.70 | MEN1 (0.55) | MAPTTP53RAB9ASMN1; SMN2HPGD | |
| SCHEMBL10079528 | 0.70 | S100A4 (0.53) | MAPTTP53RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8365427 | 0.70 | ALDH1A1 (0.58) | MAPTTP53RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018948-A2 | NOVEL TREATMENT OF PROSTATE CARCINOMA | PELLFICURE PHARMACEUTICALS, INC. (US) | 2012-02-09 | — | — | WO | disclosed |