SCHEMBL20795338

SCHEMBL20795338

COC1c2ccc(c(-c3ccccc3)c2)C1OC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 1/20 0.36
PIN1 Q13526 1/20 0.34
BACE1 P56817 2/20 0.33
SQOR Q9Y6N5 2/20 0.33
PDE4B Q07343 2/20 0.33
METAP2 P50579 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
CYP3A4 P08684 2/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2E1 P05181 1/20 0.33
CYP2C8 P10632 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP4B1 P13584 1/20 0.33
CYP2B6 P20813 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23310486 0.71 HTR2C (0.38) NPC1KDM4EMEN1KMT2AELANE
SCHEMBL20999088 0.71 PDE4B (0.39) ALDH1A1PDE4BPDE4APDE4CPDE4D
SCHEMBL19489752 0.69 POLB (0.54) ALDH1A1CYP3A4CYP1A2CYP2D6CYP2C9
SCHEMBL23114366 0.66 PTAFR (0.33) ELANE
Methoxymethane SCHEMBL27842914 0.61 ALDH1A1 (0.50) ALDH1A1HSD17B10BACE1PDE4BCYP2A6
SCHEMBL24345237 0.60 ALDH1A1 (0.43) ALDH1A1HSD17B10CYP3A4NPC1RAB9A
SCHEMBL3785577 0.59 ALDH1A1 (0.50) ALDH1A1HSD17B10PIN1BACE1CYP3A4
SCHEMBL24049723 0.59 PGR (0.56) ALDH1A1BACE1SQORPDE4BPDE4A
SCHEMBL294721 0.59 ALDH1A1 (0.58) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL13385087 0.59 PDE4B (0.48) ALDH1A1HSD17B10PDE4BPDE4APDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10224562-B2 Method for producing polymer electrolyte molded article, polymer electrolyte material, polymer electrolyte membrane, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2019-03-05 US disclosed