Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19490683 | 0.86 | PTGS2 (0.48) | SIRT2ALDH1A1HPGDMAOBCA1 | |
| SCHEMBL19490831 | 0.82 | CA12 (0.52) | SIRT2ALDH1A1HPGDCA2CA9 | |
| SCHEMBL19490690 | 0.82 | SIRT2 (0.41) | SIRT2ALDH1A1HPGDMAOBCA1 | |
| SCHEMBL31682616 | 0.81 | GRIN2D (0.53) | SIRT2ALDH1A1HPGDMAOBCA1 | |
| SCHEMBL5178571 | 0.81 | GRIN2D (0.53) | SIRT2ALDH1A1HPGDMAOBCA1 | |
| SCHEMBL9754405 | 0.81 | GRIN2D (0.53) | SIRT2ALDH1A1HPGDMAOBCA1 | |
| SCHEMBL19490691 | 0.78 | MAPT (0.47) | SIRT2ALDH1A1HPGDMAOBCA1 | |
| SCHEMBL11803784 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HPGDMAOBMAPTMEN1 | |
| SCHEMBL11803780 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HPGDMAOBMAPTMEN1 | |
| SCHEMBL18632804 | 0.75 | CA12 (0.41) | ALDH1A1HPGDCA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984079-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2020-07-01 | — | — | EP | disclosed |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | POWER OLEDS LIMITED (GB) | 2019-10-08 | — | — | US | disclosed |
| US-10364316-B2 | Conjugated polymer containing ethynyl crosslinking group, mixture, formulation, organic electronic device containing the same and application therof | GUANGZHOU CHINARAY OPTOELECTRONICS MATERIALS LTD. (CN) | 2019-07-30 | — | — | US | disclosed |
| US-9991451-B2 | Organic light-emitting device, display apparatus, image display apparatus, lighting apparatus, image formation apparatus, and exposure apparatus | CANON KABUSHIKI KAISHA (JP) | 2018-06-05 | — | — | US | disclosed |
| US-20180022865-A1 | CONJUGATED POLYMER CONTAINING ETHYNYL CROSSLINKING GROUP, MIXTURE COMPOSITION, ORGANIC ELECTRONIC DEVICE CONTINAING THE SAME AND APPLICATION THEROF | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-20170365789-A1 | COMPOUND, MIXTURE COMPRISING THE SAME, COMPOSITION AND ORGANIC ELECTRONIC DEVICE | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2017-12-21 | — | — | US | disclosed |
| EP-2232611-B1 | BARRIER COATED SUBSTRATE AND ELECTRO-OPTICAL DEVICE | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-9796684-B2 | Materials for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | NAT1, SLCO2A1, SLCO2B1 | SIRT2 1274/4885ALDH1A1 789/4885HPGD 3332/4885 |
| US-20170365789-A1 | COMPOUND, MIXTURE COMPRISING THE SAME, COMPOSITION AND ORGANIC ELECTRONIC DEVICE | DDT, DRD3, ICMT | SIRT2 275/4885ALDH1A1 2400/4885HPGD 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.