Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRB | O95718 | 1/20 | 0.47 |
| ▸ | ESRRA | P11474 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12444682 | 0.84 | ESRRB (0.48) | ESRRBESRRAADRA1AAPPCA9 | |
| SCHEMBL23579530 | 0.82 | APP (0.47) | ESRRBESRRAADRA1AAPPCA9 | |
| SCHEMBL15782525 | 0.78 | APP (0.43) | ESRRBESRRAADRA1AAPPCA9 | |
| SCHEMBL21626102 | 0.78 | APP (0.43) | ESRRBESRRAADRA1AAPPCA9 | |
| SCHEMBL21626064 | 0.78 | ESRRB (0.44) | ESRRBESRRAADRA1AAPPCA9 | |
| SCHEMBL17231342 | 0.78 | APP (0.43) | ESRRBESRRAADRA1AAPPCA9 | |
| SCHEMBL21626070 | 0.78 | APP (0.43) | ESRRBESRRAADRA1AAPPCA9 | |
| SCHEMBL13315790 | 0.78 | MIF (0.54) | HSD17B3MIFALDH1A1HPGDESR2 | |
| SCHEMBL21626101 | 0.76 | ADRA1A (0.42) | ESRRBESRRAADRA1AAPPCA9 | |
| SCHEMBL15782494 | 0.76 | ADRA1A (0.42) | ESRRBESRRAADRA1AAPPCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11167277-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2021-11-09 | — | — | US | disclosed |
| US-20200398262-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-12-24 | — | — | US | disclosed |
| US-10758895-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2020-09-01 | — | — | US | disclosed |
| US-20170297008-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCACATION (US) | 2017-10-19 | — | — | US | disclosed |
| US-20170297008-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCACATION (US) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200398262-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | RNGTT, AOC2, CTRC | ESRRB 4485/4885ESRRA 4101/4885ADRA1A 2812/4885 |
| US-10758895-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | RNGTT, AOC2, CTRC | ESRRB 4485/4885ESRRA 4101/4885ADRA1A 2812/4885 |
| US-11167277-B2 | Cu(I)-catalyzed azide-alkyne cycloadditions (CuAAC) ligands and methods for carrying out Cu(I)-catalyzed azide-alkyne cycloaddition reactions | RNGTT, AOC2, CTRC | ESRRB 4485/4885ESRRA 4101/4885ADRA1A 2812/4885 |
| US-20170297008-A1 | CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITIONS (CUAAC) LIGANDS AND METHODS FOR CARRYING OUT CU(I)-CATALYZED AZIDE-ALKYNE CYCLOADDITION REACTIONS | RNGTT, AOC2, CTRC | ESRRB 4485/4885ESRRA 4101/4885ADRA1A 2812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.