Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30151579 | 0.81 | GABRA1 (0.46) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL19491783 | 0.81 | GABRA1 (0.46) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL16245770 | 0.80 | GABRA1 (0.46) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL20875725 | 0.79 | GABRA1 (0.44) | GABRA1GABRB2S1PR1PTGS2PTGS1 | |
| SCHEMBL29362810 | 0.75 | GABRA1 (0.41) | GABRA1GABRB2S1PR1PTGS2PTGS1 | |
| SCHEMBL7149958 | 0.75 | GABRA1 (0.41) | GABRA1GABRB2S1PR1PTGS2PTGS1 | |
| SCHEMBL17748246 | 0.75 | GABRA1 (0.47) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL3074890 | 0.75 | GABRA1 (0.43) | GABRA1GABRB2S1PR1PTGS2PTGS1 | |
| SCHEMBL29394461 | 0.73 | RXRA (0.47) | GABRA1GABRB2S1PR1PTGS2PTGS1 | |
| SCHEMBL2238065 | 0.73 | RXRA (0.47) | GABRA1GABRB2S1PR1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298292-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN S.A. (CH) | 2017-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298292-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | OR10J3, C5, CBR3 | GABRA1 4012/4885GABRB2 3562/4885TYR 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.