SCHEMBL19494347

SCHEMBL19494347

Cc1ccc(CSC(=S)N2C=NCC2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
IDO1 P14902 2/20 0.41
KDM1A O60341 9/20 0.40
SMN1; SMN2 Q16637 3/20 0.37
TSHR P16473 1/20 0.37
GFER P55789 1/20 0.37
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 2/20 0.35
FAAH O00519 1/20 0.35
MGLL Q99685 1/20 0.35
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35
TUBB2A Q13885 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28355462 0.73 PKM (0.52) IDO1KDM1ASMN1; SMN2NPC1RAB9A
SCHEMBL5731404 0.71 POLB (0.44) POLBIDO1SMN1; SMN2TSHRGFER
SCHEMBL11436966 0.69 IDO1 (0.61) IDO1RAB9AALDH1A1
SCHEMBL10086570 0.67 IDO1 (0.59) POLBIDO1RAB9AALDH1A1
SCHEMBL19468243 0.67 CYP19A1 (0.46) POLBIDO1KDM1ASMN1; SMN2L3MBTL1
SCHEMBL19468205 0.66 ALDH1A1 (0.65) POLBKDM1ASMN1; SMN2ALDH1A1FAAH
SCHEMBL11436967 0.66 IDO1 (0.57) IDO1RAB9AALDH1A1
SCHEMBL16900456 0.65 MAPT (0.46) POLBIDO1L3MBTL1
Water SCHEMBL28218487 0.64 LMNA (0.44) POLBSMN1; SMN2TSHRNPC1RAB9A
SCHEMBL26554494 0.63 IDO1 (0.53) IDO1SMN1; SMN2RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3235815-A1 AGENTS AGAINST PARASITIC HELMINTHS PHILIPPS-UNIVERSITÄT MARBURG (DE) 2017-10-25 EP disclosed