Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 8/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.32 |
| ▸ | MTOR | P42345 | 4/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637508 | 0.79 | SHBG (0.45) | SHBGMAPTTDP1KDM4EADRB2 | |
| SCHEMBL881176 | 0.72 | SHBG (0.44) | SHBGMAPTTDP1KDM4EADRB2 | |
| SCHEMBL12248156 | 0.71 | SHBG (0.49) | SHBGMAPTTDP1KDM4EADRB2 | |
| SCHEMBL13912410 | 0.67 | SHBG (0.64) | SHBGMAPTTDP1KDM4EADRB2 | |
| SCHEMBL13637503 | 0.64 | SHBG (0.43) | SHBGMAPTTDP1KDM4EADRB2 | |
| SCHEMBL107203 | 0.64 | TDP1 (0.59) | MAPTTDP1KDM4EADRB2MTOR | |
| SCHEMBL13912408 | 0.63 | ALOX15 (0.59) | SHBGMAPTTDP1KDM4EMTOR | |
| SCHEMBL10582745 | 0.62 | TDP1 (0.57) | MAPTTDP1KDM4EADRB2MTOR | |
| SCHEMBL11061261 | 0.62 | SHBG (0.49) | SHBGMAPTTDP1KDM4EADRB2 | |
| SCHEMBL18479371 | 0.61 | KDM4E (0.61) | MAPTTDP1KDM4EADRB2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064251-B1 | BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR | KENSEY NASH CORP (US) | 2017-10-25 | — | — | EP | disclosed |