Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17621874 | 0.83 | MAPT (0.40) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL20435047 | 0.81 | ALDH1A1 (0.58) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL19035541 | 0.81 | APP (0.49) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL19496564 | 0.80 | ALDH1A1 (0.42) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL24728555 | 0.80 | MGLL (0.42) | KDM4ESMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL23193237 | 0.79 | ROCK2 (0.45) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL25884564 | 0.79 | TOP2A (0.47) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL27353978 | 0.79 | APP (0.44) | KMT2AMEN1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL20420548 | 0.77 | RXFP1 (0.42) | KMT2AMEN1MAPTKDM4ENPSR1 | |
| SCHEMBL24966596 | 0.75 | ALDH1A1 (0.64) | KMT2AMEN1MAPTKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3235820-A1 | PYRROLOBENZODIAZEPINES AND ANTIBODY DISULFIDE CONJUGATES THEREOF | Genentech, Inc. (US) | 2017-10-25 | — | — | EP | disclosed |