Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926429 | 0.80 | PTGS2 (0.33) | PTGS2RAPGEF4PDE2AALOX5PTGS1 | |
| SCHEMBL3214261 | 0.77 | PTGS2 (0.38) | MEN1POLBGAAKMT2APTGS2 | |
| SCHEMBL599609 | 0.75 | RAPGEF4 (0.41) | MEN1POLBGAAKMT2APTGS2 | |
| Trimethylammonium SCHEMBL28999997 | 0.74 | PTGS2 (0.42) | PTGS2TP53TRPA1CYP1A2CYP2A6 | |
| SCHEMBL18570653 | 0.72 | PTGS2 (0.37) | PTGS2RAPGEF4TP53PDE2AALOX5 | |
| SCHEMBL16116825 | 0.72 | ESR1 (0.45) | GAAPTGS2RAPGEF4PDE2AALOX5 | |
| SCHEMBL60535 | 0.71 | RAPGEF4 (0.43) | MEN1POLBGAAKMT2ARAPGEF4 | |
| SCHEMBL23457970 | 0.70 | TSHR (0.40) | PTGS2TP53 | |
| SCHEMBL8630814 | 0.70 | PTGS2 (0.36) | MEN1KMT2APTGS2RAPGEF4TP53 | |
| SCHEMBL1023068 | 0.70 | PTGS1 (0.55) | GAAPTGS2ALOX5PTGS1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2574613-B1 | Cyclometallated tetradentate Pt (II) complexes comprised of one or two imidazole rings with a twisted aryl group bonded to N-1 | UNIVERSAL DISPLAY CORP (US) | 2017-10-25 | — | — | EP | disclosed |