Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25587635 | 0.88 | ALDH1A1 (0.36) | HSPA5MEN1GAAKMT2APOLB | |
| SCHEMBL27908301 | 0.81 | HSPA5 (0.37) | PTGS2HSPA5MEN1GAAKMT2A | |
| SCHEMBL16572135 | 0.81 | MEN1 (0.31) | MEN1GAAKMT2APOLBPSMB5 | |
| SCHEMBL27908278 | 0.80 | KMT2A (0.36) | MEN1GAAKMT2APOLBPSMB5 | |
| SCHEMBL636402 | 0.79 | MEN1 (0.30) | MEN1GAAKMT2APOLB | |
| SCHEMBL637171 | 0.78 | GABRA1 (0.36) | MEN1GAAKMT2APOLBPSMB5 | |
| SCHEMBL31470101 | 0.78 | HSPA5 (0.34) | PTGS2HSPA5MEN1GAAKMT2A | |
| SCHEMBL9812178 | 0.78 | PTGS2 (0.48) | PTGS2TP53 | |
| SCHEMBL19496402 | 0.77 | MEN1 (0.41) | PTGS2MEN1GAAKMT2APOLB | |
| SCHEMBL636020 | 0.76 | MEN1 (0.31) | MEN1GAAKMT2APOLBPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222457-B2 | Coordination compounds of the boron group | CHEMETALL GMBH (DE) | 2012-07-17 | — | — | US | disclosed |
| US-20100029875-A1 | COORDINATION COMPOUNDS OF THE BORON GROUP | CHEMETALL GMBH (DE) | 2010-02-04 | — | — | US | disclosed |
| EP-2097424-A1 | COORDINATION COMPOUNDS OF THE BORON GROUP | Chemetall GmbH (DE) | 2009-09-09 | — | — | EP | disclosed |
| US-20090062497-A1 | Borate Salts, Method for the Production Thereof and Use Thereof | CHEMETALL GMBH (DE) | 2009-03-05 | — | — | US | disclosed |
| EP-1934235-A1 | BORATE SALTS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF | Chemetall GmbH (DE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2008059065-A1 | COORDINATION COMPOUNDS OF THE BORON GROUP | CHEMETALL GMBH (DE) | 2008-05-22 | — | — | WO | disclosed |
| WO-2007042500-A1 | BORATE SALTS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF | CHEMETALL GMBH (DE) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062497-A1 | Borate Salts, Method for the Production Thereof and Use Thereof | SLC6A12, TST, MPST | PTGS2 2750/4885HSPA5 405/4885MEN1 962/4885 |
| US-20100029875-A1 | COORDINATION COMPOUNDS OF THE BORON GROUP | BICRA, SOD1, NBAS | PTGS2 4439/4885HSPA5 3678/4885MEN1 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.