SCHEMBL19500796

SCHEMBL19500796

CC1(C)c2ccccc2-c2ccc(-n3c4ccccc4c4ccc(-c5ccc(-c6ccc7c8ccccc8n(-c8ccc9ccccc9c8)c7c6)cc5)cc43)cc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK10 P53779 5/20 0.34
▸ MAPK9 P45984 4/20 0.34
▸ RXRA P19793 1/20 0.33
▸ RXRB P28702 1/20 0.33
▸ TUBB4A P04350 1/20 0.32
▸ TUBB P07437 1/20 0.32
▸ TUBA3C P0DPH7 1/20 0.32
▸ TUBA1B P68363 1/20 0.32
▸ TUBA4A P68366 1/20 0.32
▸ TUBB4B P68371 1/20 0.32
▸ TUBB3 Q13509 1/20 0.32
▸ TUBB2A Q13885 1/20 0.32
▸ TUBB8 Q3ZCM7 1/20 0.32
▸ TUBA3E Q6PEY2 1/20 0.32
▸ TUBA1A Q71U36 1/20 0.32
▸ TUBA1C Q9BQE3 1/20 0.32
▸ TUBB6 Q9BUF5 1/20 0.32
▸ TUBB2B Q9BVA1 1/20 0.32
▸ TUBB1 Q9H4B7 1/20 0.32
▸ F2 P00734 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23370402 0.99 MAPK10 (0.34) MAPK10MAPK9RXRARXRBTUBB4A
SCHEMBL19061270 0.98 TUBB4A (0.34) MAPK10MAPK9RXRARXRBTUBB4A
SCHEMBL19500779 0.97 MAPK9 (0.32) MAPK10MAPK9RXRARXRBTUBB4A
SCHEMBL19500780 0.97 MAPK9 (0.32) MAPK10MAPK9RXRARXRBTUBB4A
SCHEMBL23370393 0.96 MAPK10 (0.33) MAPK10MAPK9TUBB4ATUBBTUBA3C
SCHEMBL23370395 0.96 MAPK10 (0.33) MAPK10MAPK9TUBB4ATUBBTUBA3C
SCHEMBL19500803 0.94 RXRA (0.34) RXRARXRBKDM4EATML3MBTL1
SCHEMBL23370597 0.94 PIK3CD (0.32) RXRARXRBTUBB4ATUBBTUBA3C
SCHEMBL19061505 0.94 TUBB4A (0.33) MAPK10MAPK9TUBB4ATUBBTUBA3C
SCHEMBL19061535 0.93 TUBB4A (0.34) MAPK10MAPK9TUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10633583-B2 Organic electroluminescent compounds and an organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2020-04-28 — — US disclosed
US-20170305854-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-10-26 — — US disclosed
US-20170305854-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170305854-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OTC, TELO2, TERT MAPK10 956/4885MAPK9 994/4885RXRA 2393/4885
US-10633583-B2 Organic electroluminescent compounds and an organic electroluminescent device comprising the same ELAVL1, OTC, SOD1 MAPK10 815/4885MAPK9 760/4885RXRA 1935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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