SCHEMBL195020

SCHEMBL195020

O=C(c1ccc(Cl)cc1Cl)c1ccc(Cl)cc1Cl

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.71
TSHR P16473 1/20 0.71
CASP1 P29466 1/20 0.71
SRD5A2 P31213 1/20 0.66
ALDH1A1 P00352 4/20 0.63
MAPK1 P28482 1/20 0.63
HIF1A Q16665 1/20 0.63
MAPT P10636 2/20 0.61
KDM4E B2RXH2 1/20 0.61
RAB9A P51151 1/20 0.59
HSD17B10 Q99714 1/20 0.58
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
RECQL P46063 2/20 0.55
ERCC5 P28715 1/20 0.55
FEN1 P39748 1/20 0.55
HTT P42858 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.53
POLB P06746 2/20 0.53
CYP2C9 P11712 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30185351 1.00 SMN1; SMN2 (0.71) SMN1; SMN2TSHRCASP1SRD5A2ALDH1A1
SCHEMBL29829303 0.89 RECQL (0.71) SMN1; SMN2TSHRCASP1SRD5A2ALDH1A1
SCHEMBL5080596 0.89 RECQL (0.71) SMN1; SMN2TSHRCASP1SRD5A2ALDH1A1
SCHEMBL9496067 0.87 SRD5A2 (0.79) SMN1; SMN2TSHRCASP1SRD5A2ALDH1A1
SCHEMBL11624724 0.86 RECQL (0.77) SMN1; SMN2TSHRCASP1SRD5A2ALDH1A1
SCHEMBL11849847 0.86 SMN1; SMN2 (0.55) SMN1; SMN2TSHRCASP1SRD5A2ALDH1A1
SCHEMBL9422054 0.86 SMN1; SMN2 (0.55) SMN1; SMN2TSHRCASP1SRD5A2ALDH1A1
SCHEMBL8065539 0.85 SMN1; SMN2 (0.71) SMN1; SMN2TSHRCASP1SRD5A2ALDH1A1
SCHEMBL180845 0.85 SMN1; SMN2 (0.71) SMN1; SMN2TSHRCASP1SRD5A2ALDH1A1
SCHEMBL8864622 0.84 SMN1; SMN2 (0.69) SMN1; SMN2TSHRCASP1SRD5A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110511163-B Method for preparing polyisocyanate by photochemical reaction and method for preparing aqueous polyurethane resin 万华化学集团股份有限公司 2021-09-07 CN claimed
CN-110511163-A Photochemical reaction prepares the method for polyisocyanates and prepares the method for waterborne polyurethane resin WANHUA CHEMICAL GROUP CO LTD 2019-11-29 CN claimed
CN-108864075-A A kind of isothiazole connection thiazole and its preparation method and application 南开大学 2018-11-23 CN claimed
US-20020016226-A1 UV curable coating for golf balls LORD CORPORATION 2002-02-07 US claimed
WO-1995011927-A1 POLYESTER-MODIFIED POLYDIENE/ACRYLOURETHANE OLIGOMERS LORD CORPORATION (US) 1995-05-04 WO claimed
US-4163865-A Process for the preparation of pinacols BAYER AKTIENGESELLSCHAFT (DE) 1979-08-07 US claimed
JP-58131925-A None JP disclosed
JP-60016948-A None JP disclosed
US-12552901-B2 Polyarylene sulfide production method KUREHA CORPORATION (JP) 2026-02-17 US disclosed
US-12509555-B2 Method for producing polyarylene sulfide KUREHA CORPORATION (JP) 2025-12-30 US disclosed
US-20230192958-A1 POLYARYLENE SULFIDE PRODUCTION METHOD KUREHA CORPORATION (JP) 2023-06-22 US disclosed
US-20230033026-A1 METHOD FOR PRODUCING POLYARYLENE SULFIDE KUREHA CORPORATION (JP) 2023-02-02 US disclosed
CN-115485320-A Method for producing polyarylene sulfide 株式会社吴羽 2022-12-16 CN disclosed
JP-S58131925-A PRODUCTION OF 2,2',4,4'-TETRACHLOROBENZOPHENONE DICHLORIDE ISHIHARA SANGYO KAISHA LTD 1983-08-06 JP disclosed
US-4306012-A Process of radiation and heat treatment of printing medium HERCULES INCORPORATED (US) 1981-12-15 US disclosed
US-4174218-A CROSSLINKING ADDITION POLYMER WITH SATURATED MONOMER BY PHOTOPOLYMERIZATION HERCULES INCORPORATED (US) 1979-11-13 US disclosed
US-4163865-A Process for the preparation of pinacols BAYER AKTIENGESELLSCHAFT (DE) 1979-08-07 US disclosed
US-4152441-A Analgesic imidazolemethanols GIST-BROCADES N.V. (NL) 1979-05-01 US disclosed
US-4137081-A Printing plates from polymer with terminal unsaturation HERCULES INCORPORATED (US) 1979-01-30 US disclosed
US-3956324-A THERMOPLASTIC POLYMER CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509555-B2 Method for producing polyarylene sulfide AS3MT, ZW10, POLR2H SMN1; SMN2 1790/4885TSHR 3498/4885CASP1 3640/4885
US-12552901-B2 Polyarylene sulfide production method PEAK1, POLR2H, TDO2 SMN1; SMN2 1355/4885TSHR 2455/4885CASP1 2134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.