SCHEMBL1950301

SCHEMBL1950301

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nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27310914 0.96 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL3821278 0.87 IDUA (0.31)
SCHEMBL28093271 0.87 IDUA (0.31)
SCHEMBL9556151 0.85
SCHEMBL28641674 0.83
SCHEMBL25379088 0.82
SCHEMBL28242019 0.82 IDUA (0.32)
SCHEMBL27966923 0.80
SCHEMBL28064418 0.79
SCHEMBL185267 0.79 LGALS3 (0.44) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112601555-A Compositions and methods relating to anti-CD 19 antibody drug conjugates 乐高化学生物科学股份有限公司 2021-04-02 CN claimed
EP-4635501-A2 SAPONIN DERIVATIVES WITH IMPROVED THERAPEUTIC WINDOW Sapreme Technologies B.V. (NL) 2025-10-22 EP disclosed
EP-4003427-B1 SAPONIN DERIVATIVES WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECH BV (NL) 2025-09-17 EP disclosed
EP-4282853-A1 PROCESS FOR THE PREPARATION OF MESACONIC ACID ESTERS Symrise AG (DE) 2023-11-29 EP disclosed
US-20230365617-A1 SAPONIN DERIVATIVES FOR USE IN MEDICINE SAPREME TECHNOLOGIES B.V. (NL) 2023-11-16 US disclosed
CN-115551537-A Tumor cell vaccine 纽沃进公司 2022-12-30 CN disclosed
CN-115461461-A MiRNA-193a for promoting immunogenic cell death 因特尔纳技术有限公司 2022-12-09 CN disclosed
CN-110099990-B Perfume mixture 西姆莱斯股份公司 2022-11-29 CN disclosed
CN-115322833-A Perfume mixture 西姆莱斯股份公司 2022-11-11 CN disclosed
CN-115315434-A Interleukin 15 fusion proteins and prodrugs and compositions and methods thereof 免疫靶向有限公司 2022-11-08 CN disclosed
CN-110709392-A Isoquinoline as HPK1 inhibitors 豪夫迈·罗氏有限公司 2020-01-17 CN disclosed
CN-110678466-A Naphthyridines as HPK1 inhibitors 豪夫迈·罗氏有限公司 2020-01-10 CN disclosed
EP-3559179-A1 FRAGRANCE MIXTURE Symrise AG (DE) 2019-10-30 EP disclosed
US-8404650-B2 Methods of treating cancer with doxazolidine and prodrugs thereof THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2013-03-26 US disclosed
US-20110135618-A1 METHODS OF TREATING CANCER WITH DOXAZOLIDINE AND PRODRUGS THEREOF THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2011-06-09 US disclosed
WO-2007102888-A2 METHODS OF TREATING CANCER WITH DOXAZOLIDINE AND PRODRUGS THEREOF THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2007-09-13 WO disclosed
US-7037907-B1 Estradiol conjugates and uses thereof THE UNIVERSITY OF MELBOURNE (AU) 2006-05-02 US disclosed
EP-1226154-A4 ESTRADIOL CONJUGATES AND USES THEREOF UNIV MELBOURNE (AU) 2005-03-23 EP disclosed
EP-1226154-A1 ESTRADIOL CONJUGATES AND USES THEREOF THE UNIVERSITY OF MELBOURNE (AU) 2002-07-31 EP disclosed
WO-2001027132-A1 ESTRADIOL CONJUGATES AND USES THEREOF THE UNIVERSITY OF MELBOURNE (AU) 2001-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365617-A1 SAPONIN DERIVATIVES FOR USE IN MEDICINE HAVCR2, TTR, PYGL ALDH1A1 1485/4885TSHR 182/4885HSD17B10 677/4885
US-20110135618-A1 METHODS OF TREATING CANCER WITH DOXAZOLIDINE AND PRODRUGS THEREOF DNPEP, PEPD, PREP ALDH1A1 427/4885TSHR 3888/4885HSD17B10 1830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.