SCHEMBL19503201

SCHEMBL19503201

Cc1scc(C(=O)OCc2ccccc2)c1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
TDP1 Q9NUW8 3/20 0.51
L3MBTL1 Q9Y468 4/20 0.49
TSHR P16473 4/20 0.49
MAPK1 P28482 3/20 0.49
CYP3A4 P08684 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
KMT2A Q03164 1/20 0.49
PRKCZ Q05513 2/20 0.45
LMNA P02545 1/20 0.45
RAB9A P51151 2/20 0.45
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
POLB P06746 1/20 0.45
HPGD P15428 2/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3218276 0.80 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1CYP3A4KMT2A
SCHEMBL22005506 0.78 ALDH1A1 (0.57) ALDH1A1TDP1L3MBTL1TSHRMAPK1
SCHEMBL19503204 0.77 RAB9A (0.49) ALDH1A1TDP1L3MBTL1TSHRMAPK1
SCHEMBL19503200 0.77 ALDH1A1 (0.53) ALDH1A1TDP1L3MBTL1TSHRMAPK1
SCHEMBL23812437 0.77 ALDH1A1 (0.69) ALDH1A1TDP1L3MBTL1TSHRMAPK1
SCHEMBL27530304 0.77 ALDH1A1 (0.59) ALDH1A1TDP1L3MBTL1TSHRMAPK1
SCHEMBL28845709 0.77 ALDH1A1 (0.59) ALDH1A1TDP1L3MBTL1TSHRMAPK1
SCHEMBL3217568 0.76 ALDH1A1 (0.50) ALDH1A1TDP1L3MBTL1TSHRMAPK1
SCHEMBL11441199 0.75 ALDH1A1 (0.62) ALDH1A1TDP1L3MBTL1TSHRMAPK1
SCHEMBL22807549 0.75 ALDH1A1 (0.66) ALDH1A1TDP1L3MBTL1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210047296-A1 NON-PLATINUM METAL COMPLEXES FOR EXCIMER BASED SINGLE DOPANT WHITE ORGANIC LIGHT EMITTING DIODES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2021-02-18 US disclosed
US-10793546-B2 Non-platinum metal complexes for excimer based single dopant white organic light emitting diodes ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-10-06 US disclosed
US-20170305881-A1 NON-PLATINUM METAL COMPLEXES FOR EXCIMER BASED SINGLE DOPANT WHITE ORGANIC LIGHT EMITTING DIODES UNITED STATES DEPARTMENT OF ENERGY 2017-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210047296-A1 NON-PLATINUM METAL COMPLEXES FOR EXCIMER BASED SINGLE DOPANT WHITE ORGANIC LIGHT EMITTING DIODES RUVBL2, PDCD1LG2, PDCD1 ALDH1A1 3245/4885TDP1 4172/4885L3MBTL1 219/4885
US-10793546-B2 Non-platinum metal complexes for excimer based single dopant white organic light emitting diodes RUVBL2, PDCD1LG2, RUVBL1 ALDH1A1 3254/4885TDP1 4061/4885L3MBTL1 129/4885
US-20170305881-A1 NON-PLATINUM METAL COMPLEXES FOR EXCIMER BASED SINGLE DOPANT WHITE ORGANIC LIGHT EMITTING DIODES RUVBL2, PDCD1LG2, RUVBL1 ALDH1A1 3254/4885TDP1 4061/4885L3MBTL1 129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.