SCHEMBL19503203

SCHEMBL19503203

Cc1coc(C(=O)OCc2ccccc2)c1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.49
KMT2A Q03164 2/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
ALDH1A1 P00352 5/20 0.46
LMNA P02545 1/20 0.45
RAB9A P51151 5/20 0.45
NPC1 O15118 3/20 0.45
MAPT P10636 3/20 0.45
MAPK1 P28482 2/20 0.45
STAT1 P42224 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TSHR P16473 2/20 0.44
HPGD P15428 1/20 0.43
PKM P14618 1/20 0.43
HTT P42858 1/20 0.43
CYP3A4 P08684 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
FBP1 P09467 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19503200 0.77 ALDH1A1 (0.53) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL20154268 0.75 TDP1 (0.58) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL7323211 0.75 TDP1 (0.53) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL20401024 0.75 TDP1 (0.62) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL27530304 0.74 ALDH1A1 (0.59) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL23019130 0.73 RAB9A (0.55) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL22005649 0.72 TDP1 (0.51) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL22005701 0.72 TDP1 (0.53) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL23812473 0.72 TDP1 (0.61) TDP1KMT2ASLC6A2SLC6A3ALDH1A1
SCHEMBL19503204 0.71 RAB9A (0.49) TDP1KMT2ASLC6A2SLC6A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210047296-A1 NON-PLATINUM METAL COMPLEXES FOR EXCIMER BASED SINGLE DOPANT WHITE ORGANIC LIGHT EMITTING DIODES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2021-02-18 US disclosed
US-10793546-B2 Non-platinum metal complexes for excimer based single dopant white organic light emitting diodes ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-10-06 US disclosed
US-20170305881-A1 NON-PLATINUM METAL COMPLEXES FOR EXCIMER BASED SINGLE DOPANT WHITE ORGANIC LIGHT EMITTING DIODES UNITED STATES DEPARTMENT OF ENERGY 2017-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210047296-A1 NON-PLATINUM METAL COMPLEXES FOR EXCIMER BASED SINGLE DOPANT WHITE ORGANIC LIGHT EMITTING DIODES RUVBL2, PDCD1LG2, PDCD1 TDP1 4172/4885KMT2A 1223/4885SLC6A2 2628/4885
US-10793546-B2 Non-platinum metal complexes for excimer based single dopant white organic light emitting diodes RUVBL2, PDCD1LG2, RUVBL1 TDP1 4061/4885KMT2A 1331/4885SLC6A2 2452/4885
US-20170305881-A1 NON-PLATINUM METAL COMPLEXES FOR EXCIMER BASED SINGLE DOPANT WHITE ORGANIC LIGHT EMITTING DIODES RUVBL2, PDCD1LG2, RUVBL1 TDP1 4061/4885KMT2A 1331/4885SLC6A2 2452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.