Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 16/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.69 |
| ▸ | HTR2B | P41595 | 6/20 | 0.56 |
| ▸ | HTR2C | P28335 | 4/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.55 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.55 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17243941 | 0.93 | ADORA3 (0.60) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL25565810 | 0.84 | ADORA3 (0.62) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL21939669 | 0.84 | ADORA3 (0.71) | ADORA3 | |
| SCHEMBL21257353 | 0.83 | ADORA3 (0.65) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL19807422 | 0.83 | ADORA3 (0.75) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL23097648 | 0.82 | ADORA3 (0.59) | ADORA3ADORA2A | |
| SCHEMBL22359597 | 0.82 | ADORA3 (0.59) | ADORA3ADORA2A | |
| SCHEMBL25612586 | 0.82 | ADORA3 (1.00) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL19503865 | 0.81 | ADORA3 (0.76) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL19503344 | 0.81 | ADORA3 (0.64) | ADORA3ADORA1HTR2BHTR2CADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017185061-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2017-10-26 | — | — | WO | disclosed |