Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 16/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.65 |
| ▸ | HTR2B | P41595 | 6/20 | 0.53 |
| ▸ | HTR2C | P28335 | 4/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.52 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.52 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23097519 | 0.84 | ADORA3 (0.68) | ADORA3 | |
| SCHEMBL19503864 | 0.83 | ADORA3 (0.69) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL21257360 | 0.82 | ADORA3 (0.60) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL25612586 | 0.79 | ADORA3 (1.00) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL17243941 | 0.76 | ADORA3 (0.60) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL21710870 | 0.74 | ADORA3 (0.53) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL19807417 | 0.74 | ADORA3 (0.84) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL25565810 | 0.74 | ADORA3 (0.62) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL22938079 | 0.73 | ADORA3 (0.67) | ADORA3ADORA1HTR2BHTR2CADORA2A | |
| SCHEMBL6820816 | 0.73 | YTHDC1 (0.70) | ADORA3ADORA1HTR2BHTR2CADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019157317-A1 | COMPOUNDS AND METHODS FOR TREATING ADDICTION AND RELATED DISORDERS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2019-08-15 | — | — | WO | disclosed |