Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 15/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.52 |
| ▸ | HTR2B | P41595 | 6/20 | 0.51 |
| ▸ | HTR2C | P28335 | 4/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.50 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.49 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503864 | 0.84 | ADORA3 (0.69) | ADORA3ADORA1ADORA2AHTR2BHTR2C | |
| SCHEMBL17243941 | 0.78 | ADORA3 (0.60) | ADORA3ADORA1ADORA2AHTR2BHTR2C | |
| SCHEMBL25612586 | 0.77 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AHTR2BHTR2C | |
| SCHEMBL19503344 | 0.76 | ADORA3 (0.64) | ADORA3ADORA1ADORA2AHTR2BHTR2C | |
| SCHEMBL22764891 | 0.74 | ADORA3 (0.72) | ADORA3ADORA1ADORA2AHTR2BTMIGD3 | |
| SCHEMBL21257353 | 0.74 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AHTR2BHTR2C | |
| SCHEMBL19807417 | 0.72 | ADORA3 (0.84) | ADORA3ADORA1ADORA2AHTR2BHTR2C | |
| SCHEMBL19503304 | 0.72 | P2RY1 (0.65) | ADORA3HTR2BHTR2C | |
| SCHEMBL13276340 | 0.72 | ADORA3 (0.78) | ADORA3ADORA1ADORA2AHTR2BHTR2C | |
| SCHEMBL22938079 | 0.71 | ADORA3 (0.67) | ADORA3ADORA1ADORA2AHTR2BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091791-A1 | METHODS OF TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |