Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 4/20 | 0.36 |
| ▸ | CHRNA6 | Q15825 | 4/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27022736 | 0.87 | HPGD (0.38) | HPGDSMN1; SMN2RECQLATMNPC1 | |
| SCHEMBL24707744 | 0.82 | CHRNB2 (0.50) | HPGDSMN1; SMN2CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL19498126 | 0.81 | GRM5 (0.36) | HPGDSMN1; SMN2ATMNPC1RAB9A | |
| SCHEMBL25143661 | 0.79 | ALDH1A1 (0.52) | HPGDSMN1; SMN2RECQLHRH3CHRNB2 | |
| SCHEMBL27022710 | 0.79 | HPGD (0.42) | HPGDSMN1; SMN2RECQLHRH3CHRNB2 | |
| SCHEMBL10205143 | 0.78 | HPGD (0.55) | HPGDSMN1; SMN2RECQLNPC1RAB9A | |
| SCHEMBL20746951 | 0.78 | HPGD (0.61) | HPGDSMN1; SMN2RECQLATMNPC1 | |
| SCHEMBL18051840 | 0.78 | HSD11B1 (0.60) | SMN1; SMN2NPC1RAB9AKMT2ACHRNB2 | |
| SCHEMBL23776750 | 0.77 | HRH3 (0.56) | HPGDSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL21569674 | 0.77 | HSD11B1 (0.43) | HPGDSMN1; SMN2RECQLHRH3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305922-A1 | CARM1 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305922-A1 | CARM1 INHIBITORS AND USES THEREOF | CARM1, ADRM1, PRMT1 | HPGD 4411/4885SMN1; SMN2 1375/4885RECQL 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.