Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.33 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19505770 | 0.92 | FKBP1A (0.36) | SPHK1SPHK2CNR1CNR2DAGLA | |
| SCHEMBL19505769 | 0.89 | MGLL (0.35) | PNLIPCNR1CNR2DAGLA | |
| SCHEMBL21041357 | 0.88 | PNLIP (0.30) | PNLIP | |
| SCHEMBL19505799 | 0.87 | MAPT (0.34) | PNLIPCNR1CNR2DAGLAPDCD4 | |
| SCHEMBL19505781 | 0.86 | NAAA (0.33) | PNLIPCNR1CNR2DAGLAPDCD4 | |
| SCHEMBL19505778 | 0.86 | NAAA (0.33) | PNLIPCNR1CNR2DAGLAPDCD4 | |
| SCHEMBL19505787 | 0.84 | FKBP1A (0.40) | — | |
| SCHEMBL19505766 | 0.83 | FKBP1A (0.34) | PNLIPCNR1CNR2 | |
| SCHEMBL20996806 | 0.83 | FKBP1A (0.34) | PNLIPCNR1CNR2 | |
| SCHEMBL20996812 | 0.83 | PPARA (0.33) | PNLIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184558-A1 | NOVEL PROMYSALIN ANALOGUES AND METHODS OF USE THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-10-26 | — | — | WO | disclosed |