SCHEMBL49512

SCHEMBL49512

O=C(O)c1cc2cc(O)c(O)cc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 1.00
SMAD3 P84022 1/20 0.61
KDM4E B2RXH2 3/20 0.55
HSD17B10 Q99714 3/20 0.55
DAO P14920 3/20 0.55
HPGD P15428 2/20 0.55
MAPT P10636 1/20 0.55
SRD5A2 P31213 1/20 0.55
NFKB1 P19838 2/20 0.55
ALDH1A1 P00352 2/20 0.55
LMNA P02545 2/20 0.55
F7 P08709 1/20 0.55
F3 P13726 1/20 0.55
PIN1 Q13526 1/20 0.55
PDPK1 O15530 1/20 0.55
TSHR P16473 1/20 0.55
APEX1 P27695 1/20 0.55
CYP2C19 P33261 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
CA12 O43570 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9279858 0.87 GPR35 (0.75) GPR35SMAD3KDM4EHSD17B10DAO
SCHEMBL19332155 0.85 GPR35 (0.73) GPR35SMAD3KDM4EHSD17B10DAO
SCHEMBL7040376 0.85 GPR35 (0.73) GPR35SMAD3KDM4EHSD17B10DAO
SCHEMBL9442095 0.83 GPR35 (0.69) GPR35SMAD3KDM4EHSD17B10DAO
SCHEMBL24149191 0.82 GPR35 (0.69) GPR35SMAD3KDM4EHSD17B10DAO
SCHEMBL3361096 0.81 GPR35 (0.67) GPR35SMAD3KDM4EHSD17B10DAO
SCHEMBL19506405 0.81 GPR35 (0.67) GPR35SMAD3KDM4EHSD17B10DAO
SCHEMBL30779684 0.81 GPR35 (0.67) GPR35SMAD3KDM4EHSD17B10DAO
SCHEMBL6285596 0.81 GPR35 (0.67) GPR35SMAD3KDM4EHSD17B10DAO
SCHEMBL29379466 0.81 GPR35 (0.67) GPR35SMAD3KDM4EHSD17B10DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2416 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080487-A Preparation method of melanin-like modified cellulose composite aerogel 2026-05-26 CN claimed
WO-2026105476-A1 METHOD FOR PRODUCING PROCESSED FIBERS 花王株式会社 2026-05-21 WO claimed
WO-2026105475-A1 METHOD FOR PRODUCING PROCESSED FIBERS 花王株式会社 2026-05-21 WO claimed
CN-122005359-A Hair dye integrating dyeing and protecting functions and preparation method thereof 广州市圣莎拉化妆品有限公司 2026-05-12 CN claimed
US-12330187-B2 UV-overprotecting iridescent colored contact lenses THE UNIVERSITY OF AKRON (US) 2025-06-17 US claimed
CN-119587395-A Two-part hair dye and application method thereof 北京芙洛迪科技有限公司 2025-03-11 CN claimed
US-20250057874-A1 SYNTHETIC MELANIN NANOPARTICLES AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-20 US claimed
CN-119235680-A Composite single-agent type melanin precursor hair dye for nourishing and protecting hair 广州市清扬精细化工有限公司 2025-01-03 CN claimed
WO-2024258193-A1 METAL-PHENOL COMPLEX AND DYEING COMPOSITION COMPRISING MELANIN OR PRECURSOR THEREOF 코스맥스 주식회사 2024-12-19 WO claimed
US-12115183-B2 Synthetic melanin nanoparticles and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-10-15 US claimed
EP-0416962-A1 Keratinous fibers dyeing process with indole dyes and oxidation dye precursors and dyeing agents L'OREAL (FR) 1991-03-13 EP claimed
EP-0415802-A1 Keratinous fibres dyeing process with monohydroxyindole and hydroxyindole-5,6-disubstituted and composition L'OREAL (FR) 1991-03-06 EP claimed
EP-0414585-A1 Keratinous fibres dye composition containing an indole dye and at least a paraphenylenediamine having a secondary amino group and process L'OREAL (FR) 1991-02-27 EP claimed
US-4968497-A Skin tanning composition and method CLAIROL INCORPORATED (US) 1990-11-06 US claimed
EP-0378937-A1 Process for dyeing keratinous fibres with indole derivatives associated with nitrite, and compositions therefor L'OREAL (FR) 1990-07-25 EP claimed
EP-0376776-A2 Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone L'OREAL (FR) 1990-07-04 EP claimed
EP-0356119-A1 Skin tanning composition and method Bristol-Myers Company (US) 1990-02-28 EP claimed
US-4885006-A Process for dyeing keratinous fibres with indole derivatives combined with an iodide L'OREAL (FR) 1989-12-05 US claimed
EP-0342034-A2 Process for dyeing hair by the sequential treatment with metal ion containing composition and dye composition containing 5,6-dihydroxyindole-2-carboxylic acid Bristol-Myers Squibb Company (US) 1989-11-15 EP claimed
CN-87107844-A Carry out the method for dyeing keratinous fibres with indole derivatives and iodide 1988-07-13 CN claimed