Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1577705 | 0.93 | GPR119 (0.62) | GPR119MAPTTP53ALDH1A1HPGD | |
| SCHEMBL1577956 | 0.91 | GPR119 (0.60) | GPR119MAPTTP53ALDH1A1HPGD | |
| SCHEMBL1118366 | 0.83 | GPR119 (0.71) | GPR119MAPTTP53ALDH1A1POLB | |
| Mbx-2982 SCHEMBL1118326 | 0.83 | GPR119 (1.00) | GPR119ALDH1A1KMT2AMEN1ALOX15 | |
| Mbx-2982 SCHEMBL1662567 | 0.83 | GPR119 (0.98) | GPR119ALDH1A1KMT2AMEN1ALOX15 | |
| SCHEMBL21397888 | 0.81 | GPR119 (0.73) | GPR119MAPTTP53ALDH1A1POLB | |
| SCHEMBL1118200 | 0.80 | GPR119 (0.91) | GPR119MAPTRXRAGRIN1GRIN2B | |
| SCHEMBL10179657 | 0.80 | GPR119 (0.52) | GPR119MAPTALDH1A1TDP1 | |
| SCHEMBL1577822 | 0.80 | GPR119 (0.53) | GPR119MAPTALDH1A1HPGDPOLB | |
| SCHEMBL1577792 | 0.80 | GPR119 (0.57) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018537-A1 | GPR119 AGONIST | NIPPON CHEMIPHAR CO., LTD. (JP) | 2014-01-16 | — | — | US | disclosed |
| US-8536176-B2 | GPR119 agonist | NIPPON CHEMIPHAR CO., LTD. (JP) | 2013-09-17 | — | — | US | disclosed |
| US-20110137032-A1 | GPR119 AGONIST | NIPPON CHEMIPHAR CO., LTD. (JP) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018537-A1 | GPR119 AGONIST | GPR119, GPR27, GPR52 | GPR119 1/4885MAPT 4853/4885TP53 4370/4885 |
| US-20110137032-A1 | GPR119 AGONIST | GPR119, GPR27, GPR52 | GPR119 1/4885MAPT 4853/4885TP53 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.