Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.60 |
| ▸ | ITGAV | P06756 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19509033 | 0.93 | MEN1 (0.57) | ITGB3ITGA2BMEN1KMT2APTGES | |
| SCHEMBL3643477 | 0.89 | ITGB3 (0.58) | ITGB3ITGA2BITGAVMEN1KMT2A | |
| SCHEMBL3643481 | 0.89 | ITGB3 (0.58) | ITGB3ITGA2BITGAVMEN1KMT2A | |
| SCHEMBL18244718 | 0.87 | MEN1 (0.53) | ITGB3ITGA2BITGAVMEN1KMT2A | |
| SCHEMBL7295683 | 0.86 | MEN1 (0.56) | ITGB3ITGA2BITGAVMEN1KMT2A | |
| SCHEMBL7295680 | 0.86 | MEN1 (0.56) | ITGB3ITGA2BITGAVMEN1KMT2A | |
| SCHEMBL16119287 | 0.85 | PTPN1 (0.52) | ITGB3ITGA2BMEN1KMT2APTGES | |
| SCHEMBL10349352 | 0.85 | ITGB3 (0.78) | ITGB3ITGA2BITGAVCTSLCTSS | |
| SCHEMBL17695752 | 0.83 | CNR2 (0.48) | ITGB3ITGA2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8005589 | 0.83 | ITGB3 (0.61) | ITGB3ITGA2BPTGESALOX5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184871-A1 | CARBIDOPA AND L-DOPA PRODRUGS AND METHODS OF USE | ABBVIE INC. (US) | 2017-10-26 | — | — | WO | disclosed |