Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19509029 | 0.93 | ITGB3 (0.60) | MEN1KMT2APTGESALOX5PPARG | |
| SCHEMBL17695752 | 0.90 | CNR2 (0.48) | MEN1KMT2ACNR2ALDH1A1ALOX15 | |
| SCHEMBL17695789 | 0.87 | MEN1 (0.46) | MEN1KMT2ACNR2ALDH1A1ALOX15 | |
| SCHEMBL17695787 | 0.87 | MEN1 (0.46) | MEN1KMT2ACNR2ALDH1A1ALOX15 | |
| SCHEMBL3131881 | 0.87 | ITGB3 (0.67) | ALDH1A1ALOX15PPARGITGB3ITGA2B | |
| SCHEMBL16119287 | 0.86 | PTPN1 (0.52) | MEN1KMT2APTGESALOX5PPARG | |
| SCHEMBL8668133 | 0.85 | SIRT2 (0.52) | CNR2ALDH1A1ALOX15ITGB3ITGA2B | |
| SCHEMBL29561342 | 0.84 | MEN1 (0.53) | MEN1KMT2AALDH1A1ALOX15ITGB3 | |
| SCHEMBL16315984 | 0.83 | ITGB3 (0.49) | CNR2PTGESALOX5PPARGITGB3 | |
| SCHEMBL8005403 | 0.83 | ITGB3 (0.49) | CNR2PTGESALOX5PPARGITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184871-A1 | CARBIDOPA AND L-DOPA PRODRUGS AND METHODS OF USE | ABBVIE INC. (US) | 2017-10-26 | — | — | WO | disclosed |