Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KYNU | Q16719 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668099 | 0.90 | MEN1 (0.54) | ALDH1A1ALOX15CTSLCTSSLMNA | |
| SCHEMBL19509033 | 0.85 | MEN1 (0.57) | SIRT2SIRT1SIRT3ALDH1A1ALOX15 | |
| SCHEMBL8669583 | 0.85 | CTRB1 (0.49) | ALDH1A1CTSLCTSSMAPTCTSK | |
| SCHEMBL3131881 | 0.84 | ITGB3 (0.67) | ALDH1A1ALOX15CTSLCTSSCTSK | |
| SCHEMBL9306283 | 0.81 | ITGB3 (0.49) | ALDH1A1ALOX15CTSLLMNAMAPT | |
| SCHEMBL5194026 | 0.81 | SIRT2 (0.56) | SIRT2SIRT1SIRT3ALDH1A1ALOX15 | |
| SCHEMBL30070644 | 0.80 | LMNA (0.60) | ALDH1A1ALOX15CTSLCTSSLMNA | |
| SCHEMBL8674043 | 0.80 | ALDH1A1 (0.58) | ALDH1A1ALOX15CTSLCTSSLMNA | |
| SCHEMBL30825625 | 0.80 | ALDH1A1 (0.58) | ALDH1A1ALOX15CTSLCTSSLMNA | |
| SCHEMBL8335080 | 0.80 | ITGB3 (0.64) | ALDH1A1ALOX15ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5853699-A | Use of tetra azacycle complexes as x-ray diagnostic agents for the liver and gallbladder | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-29 | — | — | US | disclosed |
| EP-0794800-A1 | USE OF CHELATE COMPOUNDS AS DIAGNOSTIC AGENTS IN THE X-RAY EXAMINATION OF LIVER AND BILE DUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996016678-A1 | USE OF CHELATE COMPOUNDS AS DIAGNOSTIC AGENTS IN THE X-RAY EXAMINATION OF LIVER AND BILE DUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-06-06 | — | — | WO | disclosed |