Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16147061 | 0.85 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL15648853 | 0.85 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL27437026 | 0.83 | MEN1 (0.45) | KMT2AMEN1SMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL19500377 | 0.81 | KMT2A (0.41) | KMT2AMEN1SMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL22131563 | 0.77 | EPHX2 (0.42) | KMT2AMEN1SMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL27437149 | 0.76 | MEN1 (0.41) | KMT2AMEN1SMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL10759080 | 0.75 | SMN1; SMN2 (0.47) | KMT2AMEN1SMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL1524675 | 0.72 | GRIN2D (0.46) | KMT2AMEN1SMN1; SMN2EPHX2ALDH1A1 | |
| SCHEMBL13780945 | 0.72 | MEN1 (0.49) | KMT2AMEN1EPHX2ALDH1A1GRIN2D | |
| SCHEMBL25836653 | 0.72 | GRIN2D (0.46) | KMT2AMEN1SMN1; SMN2EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170307614-A1 | Small-Molecule Hydrophobic Tagging of Fusion Proteins and Induced Degradation of Same | UNIV YALE (US) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170307614-A1 | Small-Molecule Hydrophobic Tagging of Fusion Proteins and Induced Degradation of Same | HSP90B1, LAMP2, PSMG3 | KMT2A 3767/4885MEN1 2899/4885SMN1; SMN2 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.