Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24262379 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL38654908 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL30093387 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL24793189 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL16359229 | 0.80 | EPHX1 (0.55) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL19500429 | 0.80 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL19538718 | 0.78 | EPHX1 (0.49) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL24243983 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL21224801 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3219761 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200031862-A1 | LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS | DICERNA PHARMACEUTICALS, INC. | 2020-01-30 | — | — | US | disclosed |
| US-20170305956-A1 | Ligand-Modified Double-Stranded Nucleic Acids | NOVO NORDISK A/S (DK) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031862-A1 | LIGAND-MODIFIED DOUBLE-STRANDED NUCLEIC ACIDS | ADAR, NCL, SSU72 | SMN1; SMN2 1237/4885ALDH1A1 3796/4885POLB 177/4885 |
| US-20170305956-A1 | Ligand-Modified Double-Stranded Nucleic Acids | ADAR, NCL, SSU72 | SMN1; SMN2 1237/4885ALDH1A1 3796/4885POLB 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.