Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580792 | 0.87 | NPSR1 (0.55) | NPSR1THRATHRBFFAR1FFAR4 | |
| SCHEMBL38655010 | 0.87 | KEAP1 (0.48) | NPSR1THRATHRBFFAR1FFAR4 | |
| SCHEMBL30536049 | 0.83 | KDM4E (0.64) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL1206210 | 0.79 | ACLY (0.48) | NPSR1THRATHRBFFAR1FFAR4 | |
| SCHEMBL19731254 | 0.79 | GAA (0.57) | ALDH1A1LMNAGAAMAPTNPSR1 | |
| SCHEMBL11241194 | 0.78 | NPSR1 (0.46) | NPSR1THRATHRBFFAR1FFAR4 | |
| SCHEMBL10990753 | 0.78 | NPSR1 (0.46) | NPSR1THRATHRBFFAR1FFAR4 | |
| SCHEMBL18258239 | 0.77 | NPSR1 (0.57) | NPSR1THRATHRBFFAR1FFAR4 | |
| SCHEMBL7282363 | 0.77 | SKP2 (0.56) | NPSR1FFAR1FFAR4KEAP1CA1 | |
| SCHEMBL39866 | 0.77 | GAA (0.55) | ALDH1A1LMNAGAAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184564-A1 | SENSORS AND SENSOR ARRAYS FOR DETECTION OF ANALYTES | ICAGEN, INC. (US) | 2017-10-26 | — | — | WO | disclosed |