SCHEMBL18258239

SCHEMBL18258239

Cc1cc(CCC(=O)O)cc(C)c1C

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.57
KEAP1 Q14145 1/20 0.50
FFAR4 Q5NUL3 3/20 0.49
THRA P10827 4/20 0.48
THRB P10828 4/20 0.48
FFAR1 O14842 10/20 0.47
FABP4 P15090 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21346911 0.87 NPSR1 (0.48) NPSR1KEAP1FFAR4THRATHRB
SCHEMBL3580792 0.85 NPSR1 (0.55) NPSR1KEAP1FFAR4THRATHRB
SCHEMBL12560457 0.84 FFAR4 (0.48) NPSR1FFAR4FFAR1
SCHEMBL27846789 0.83 NPSR1 (0.53) NPSR1KEAP1FFAR4THRATHRB
SCHEMBL3669296 0.82 NPSR1 (0.52) NPSR1KEAP1FFAR4THRATHRB
SCHEMBL5670212 0.81 KEAP1 (0.64) NPSR1KEAP1FFAR4THRATHRB
SCHEMBL17586718 0.80 NPSR1 (0.50) NPSR1KEAP1FFAR4THRATHRB
SCHEMBL28172391 0.80 NPSR1 (0.50) NPSR1KEAP1FFAR4THRATHRB
SCHEMBL5846204 0.80 FFAR1 (0.61) NPSR1KEAP1FFAR4THRATHRB
SCHEMBL585200 0.79 NPSR1 (0.48) NPSR1KEAP1FFAR4THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739223-B2 Surface primer compositions and methods of use ENVISTA (US) 2023-08-29 US disclosed
US-20170217999-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE ORMCO CORPORATION 2017-08-03 US disclosed
US-20170217997-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE ORMCO CORPORATION 2017-08-03 US disclosed
WO-2016184932-A1 STABILIZATION OF HOT MELT ADHESIVES BASF SE (DE) 2016-11-24 WO disclosed
US-20070213333-A1 Substituted arylalkanoic acid derivatives and use thereof ASAHI KASEI PHAMA CORPORATION (JP) 2007-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170217999-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, GRIN1 NPSR1 1446/4885KEAP1 2655/4885FFAR4 3195/4885
US-11739223-B2 Surface primer compositions and methods of use SP1, GPER1, GRIN1 NPSR1 1446/4885KEAP1 2655/4885FFAR4 3195/4885
US-20170217997-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, ESR1 NPSR1 1766/4885KEAP1 1178/4885FFAR4 3270/4885
US-20070213333-A1 Substituted arylalkanoic acid derivatives and use thereof CYSLTR1, CYSLTR2, LTB4R2 NPSR1 132/4885KEAP1 603/4885FFAR4 35/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.