Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21912591 | 0.81 | ACHE (0.39) | ACHEPTGS2SMN1; SMN2TSHRPTGS1 | |
| SCHEMBL8272774 | 0.77 | ALDH1A1 (0.42) | ACHESMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL13811027 | 0.74 | MAP4K4 (0.40) | SMN1; SMN2TSHRALDH1A1LMNAMAPT | |
| SCHEMBL14403319 | 0.71 | TP53 (0.52) | ALDH1A1MAPT | |
| SCHEMBL12849546 | 0.70 | KDM1A (0.37) | — | |
| SCHEMBL168684 | 0.69 | — | — | |
| SCHEMBL91411 | 0.69 | — | — | |
| SCHEMBL29370717 | 0.69 | — | — | |
| SCHEMBL24283462 | 0.68 | ALDH1A1 (0.40) | TSHRALDH1A1SLC6A4 | |
| SCHEMBL12319312 | 0.68 | ERN1 (0.36) | TSHRMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4209230-A1 | MESOPOROUS SILICA NANOPARTICLE CONTROLLED RELEASE SYSTEM, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | East China University of Science and Technology (CN) | 2023-07-12 | — | — | EP | disclosed |
| US-9801882-B2 | Phosphodiesterase-1 inhibitors and their use in treatment of cardiovascular diseases | INTRA-CELLULAR THERAPIES, INC. (US) | 2017-10-31 | — | — | US | disclosed |