Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21912591 | 0.74 | ACHE (0.39) | — | |
| SCHEMBL12319312 | 0.71 | ERN1 (0.36) | EGFRKDR | |
| SCHEMBL19522683 | 0.70 | ACHE (0.39) | — | |
| SCHEMBL22166130 | 0.70 | GABRA1 (0.34) | — | |
| SCHEMBL29350499 | 0.69 | — | — | |
| SCHEMBL14413 | 0.69 | — | — | |
| SCHEMBL157146 | 0.69 | — | — | |
| SCHEMBL29570973 | 0.69 | — | — | |
| SCHEMBL13811027 | 0.68 | MAP4K4 (0.40) | — | |
| SCHEMBL2913077 | 0.67 | ALDH1A1 (0.48) | KDM1AKCNH2KDM1BKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012093809-A2 | NEW BICYCLIC COMPOUND FOR MODULATING G PROTEIN-COUPLED RECEPTORS | HANMI PHARM CO., LTD. (KR) | 2012-07-12 | — | — | WO | disclosed |