Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19669659 | 0.81 | NAAA (0.61) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL61528 | 0.81 | NAAA (0.61) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL7484827 | 0.81 | NAAA (0.61) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL1810307 | 0.79 | SMN1; SMN2 (0.61) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL19002780 | 0.78 | NAAA (0.54) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL517349 | 0.78 | NAAA (0.73) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL8690270 | 0.78 | NAAA (0.73) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL19322417 | 0.78 | CHRNB2 (0.44) | NAAASMN1; SMN2HSD17B10TSHRKMT2A | |
| SCHEMBL19757607 | 0.76 | EPHX1 (0.65) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL3184451 | 0.76 | NAAA (0.66) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9802958-B2 | Tetrahydro[1,8]naphthyridine sulfonamide and related compounds for use as agonists of RORy and the treatment of disease | LYCERA CORPORATION (US) | 2017-10-31 | — | — | US | disclosed |