Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288344 | 0.81 | CA2 (0.48) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL14273283 | 0.79 | CSNK2A1 (0.51) | KMT2AMEN1SMN1; SMN2HPGDGLA | |
| SCHEMBL26447172 | 0.76 | RAB9A (0.50) | HTTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2093081 | 0.74 | GAA (0.45) | HTTKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8042030 | 0.73 | HSD17B10 (0.46) | ALDH1A1TP53HSD17B10GAATTR | |
| SCHEMBL14551877 | 0.73 | CA12 (0.41) | HTTKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL14201716 | 0.73 | ALDH1A1 (0.52) | ALDH1A1HPGD | |
| SCHEMBL2096187 | 0.72 | MAOB (0.56) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2489812 | 0.72 | CYP3A4 (0.46) | HTTKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL1138419 | 0.72 | SMN1; SMN2 (0.52) | HTTKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611174-A1 | [1,2,4]TRIAZOLO[1,5-C]PYRIMIDINE DERIVATIVE AS A2A RECEPTOR INHIBITOR | Medshine Discovery Inc. (CN) | 2020-02-19 | — | — | EP | disclosed |
| EP-3013823-B1 | IMIDAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| CN-1972695-A | Treatment or prevention of skin conditions or tissue conditions in animals using boryloxypyridylmethanones | ANACOR PHARMACEUTICALS INC (US) | 2007-05-30 | — | — | CN | disclosed |