Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 9/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.44 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.44 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288344 | 0.78 | CA2 (0.48) | ALDH1A1TSHRHPGD | |
| SCHEMBL12690837 | 0.77 | TUBB1 (0.51) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL1647101 | 0.77 | BACE1 (0.60) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL29953580 | 0.77 | BACE1 (0.60) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL10849623 | 0.75 | ALDH1A1 (0.86) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL172939 | 0.75 | ALDH1A1 (0.71) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL1662997 | 0.75 | ALDH1A1 (0.70) | ALDH1A1TSHRKDM4ETDP1TRIM24 | |
| SCHEMBL419596 | 0.75 | ALDH1A1 (0.57) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL29392394 | 0.75 | ALDH1A1 (0.71) | ALDH1A1TSHRKDM4ETDP1ERN1 | |
| SCHEMBL1987664 | 0.74 | CA12 (0.67) | ALDH1A1TSHRKDM4ETDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057468-A1 | SMALL ORGANIC MOLECULE REGULATORS OF CELL PROLIFERATION | CURIS, INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008057469-A1 | SMALL ORGANIC MOLECULE REGULATORS OF CELL PROLIFERATION | WYETH (US) | 2008-05-15 | — | — | WO | disclosed |