Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1952608 | 1.00 | MAPT (0.44) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL6883354 | 1.00 | MAPT (0.44) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL10166818 | 0.87 | LTA4H (0.36) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL20496961 | 0.87 | NOS1 (0.40) | CYP3A4LTA4HNOS1NOS3NOS2 | |
| SCHEMBL16418495 | 0.84 | MAPT (0.47) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL16421121 | 0.84 | MAPT (0.47) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL12549290 | 0.83 | MAPT (0.46) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL24298179 | 0.82 | ALDH1A1 (0.51) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL7872976 | 0.82 | ALDH1A1 (0.51) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 | |
| SCHEMBL1128635 | 0.82 | ALDH1A1 (0.51) | MAPTALDH1A1USP2CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927484-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20110135599-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110135599-A1 | ANTIVIRAL COMPOUNDS | EIF2AK2, MAVS, HAVCR2 | MAPT 4252/4885ALDH1A1 3535/4885USP2 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.