Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22082941 | 0.80 | ALDH1A1 (0.41) | MKNK1MKNK2ALDH1A1CYP1A2RAB9A | |
| SCHEMBL19529125 | 0.80 | KMO (0.41) | MKNK1MKNK2ALDH1A1NPC1RAB9A | |
| SCHEMBL15434187 | 0.79 | MEN1 (0.35) | CYP1A2LMNAMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL19529461 | 0.79 | ALDH1A1 (0.41) | MKNK1MKNK2ALDH1A1CYP11B2MAPT | |
| SCHEMBL19942600 | 0.79 | ALDH1A1 (0.39) | MKNK1MKNK2ALDH1A1RAB9ACYP11B2 | |
| SCHEMBL25726910 | 0.74 | KMO (0.43) | MKNK1MKNK2ALDH1A1LMNAGAA | |
| SCHEMBL19142681 | 0.73 | SMN1; SMN2 (0.36) | ALDH1A1CYP1A2NPC1RAB9AMAPT | |
| SCHEMBL19942686 | 0.72 | KMO (0.51) | MKNK1MKNK2ALDH1A1CYP1A2CYP11B2 | |
| SCHEMBL22328707 | 0.71 | CES2 (0.37) | ALDH1A1NPC1RAB9ALMNAMAPT | |
| SCHEMBL13187807 | 0.71 | MKNK1 (0.50) | MKNK1MKNK2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240057-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | Hodogaya Chemical Co., Ltd. (JP) | 2017-11-01 | — | — | EP | disclosed |