Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.49 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.46 |
| ▸ | GLP1R | P43220 | 8/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409031 | 1.00 | OTC (0.49) | OTCDDAH1GLP1RNOD1TSHR | |
| SCHEMBL19019937 | 0.99 | OTC (0.50) | OTCDDAH1GLP1RNOD1TSHR | |
| SCHEMBL1951953 | 0.99 | OTC (0.50) | OTCDDAH1GLP1RNOD1TSHR | |
| SCHEMBL24788157 | 0.97 | OTC (0.47) | OTCDDAH1GLP1RNOD1TSHR | |
| SCHEMBL24788082 | 0.92 | GLP1R (0.45) | OTCDDAH1GLP1RNOD1TSHR | |
| SCHEMBL3043120 | 0.90 | DDAH1 (0.43) | OTCDDAH1GLP1RTSHRNOS3 | |
| SCHEMBL24229748 | 0.89 | OTC (0.49) | OTCDDAH1GLP1RNOD1TSHR | |
| SCHEMBL21738833 | 0.89 | OTC (0.49) | OTCDDAH1GLP1RNOD1TSHR | |
| SCHEMBL17346257 | 0.89 | OTC (0.49) | OTCDDAH1GLP1RNOD1TSHR | |
| SCHEMBL29221102 | 0.89 | OTC (0.49) | OTCDDAH1GLP1RNOD1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730912-B2 | Template-fixed peptidomimetics with antimicrobial activity | POLYPHOR LTD. (CH) | 2020-08-04 | — | — | US | disclosed |
| US-10562933-B2 | Template-fixed beta-hairpin peptidomimetics with protease inhibitory activity | POLYPHOR LTD. (CH) | 2020-02-18 | — | — | US | disclosed |
| US-20190002498-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | POLYPHOR LTD (CH) | 2019-01-03 | — | — | US | disclosed |
| US-10100084-B2 | Template-fixed beta-hairpin peptidomimetics with protease inhibitory activity | POLYPHOR LTD. (CH) | 2018-10-16 | — | — | US | disclosed |
| US-20170107259-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIMICROBIAL ACTIVITY | POLYPHOR LTD. (CH) | 2017-04-20 | — | — | US | disclosed |
| US-9596852-B2 | Template-fixed peptidomimetics with antimicrobial activity | POLYPHOR LTD. (CH) | 2017-03-21 | — | — | US | disclosed |
| US-9538752-B2 | Template-fixed peptidomimetics with antimicrobial activity | POLYPHOR LTD. (CH) | 2017-01-10 | — | — | US | disclosed |
| US-9521846-B2 | Template-fixed peptidomimetics with antimicrobial activity | POLYPHOR LTD. (CH) | 2016-12-20 | — | — | US | disclosed |
| US-9518092-B2 | Template-fixed beta-hairpin peptidomimetics with CXCR4 antagonizing activity | POLYPHOR LTD. (CH) | 2016-12-13 | — | — | US | disclosed |
| US-20160333051-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | POLYPHOR LTD (CH) | 2016-11-17 | — | — | US | disclosed |
| EP-1979374-A2 | TEMPLATE-FIXED PEPTIDOMIMETICS | Polyphor Ltd. (CH) | 2008-10-15 | — | — | EP | disclosed |
| EP-1879911-A1 | DYE CONJUGATES OF TEMPLATE-FIXED PEPTIDOMIMETICS | Polyphor Ltd. (CH) | 2008-01-23 | — | — | EP | disclosed |
| EP-1856140-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | Polyphor Ltd. (CH) | 2007-11-21 | — | — | EP | disclosed |
| WO-2007079597-A1 | TEMPLATE - FIXED PEPTIDOMIMETICS WITH ANTIMICROBIAL ACTIVITY | POLYPHOR LTD. (CH) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007079605-A2 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIMICROBIAL ACTIVITY | POLYPHOR LTD. (CH) | 2007-07-19 | — | — | WO | disclosed |
| US-20070078079-A1 | Template-fixed beta-hairpin peptidomimetics with cxcr4 antagonizing activity | POLYPHOR LTD. (CH) | 2007-04-05 | — | — | US | disclosed |
| WO-2006117011-A1 | DYE CONJUGATES OF TEMPLATE-FIXED PEPTIDOMIMETICS | POLYPHOR LTD. (CH) | 2006-11-09 | — | — | WO | disclosed |
| WO-2006087001-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | POLYPHOR LTD. (CH) | 2006-08-24 | — | — | WO | disclosed |
| EP-1622931-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH CXCR4 ANTAGONIZING ACTIVITY | Polyphor AG (CH) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004096840-A1 | TEMPLATE- FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH CXCR4 ANTAGONIZING ACTIVITY | POLYPHOR AG (CH) | 2004-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078079-A1 | Template-fixed beta-hairpin peptidomimetics with cxcr4 antagonizing activity | CXCR4, CXCL12, CCR5 | OTC 4315/4885DDAH1 2481/4885GLP1R 324/4885 |
| US-10100084-B2 | Template-fixed beta-hairpin peptidomimetics with protease inhibitory activity | CTSG, CTRL, PREP | OTC 4023/4885DDAH1 932/4885GLP1R 662/4885 |
| US-20190002498-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | CTSG, CTRL, PREP | OTC 4023/4885DDAH1 932/4885GLP1R 662/4885 |
| US-20160333051-A1 | TEMPLATE-FIXED BETA-HAIRPIN PEPTIDOMIMETICS WITH PROTEASE INHIBITORY ACTIVITY | CTSG, CTRL, PREP | OTC 4023/4885DDAH1 932/4885GLP1R 662/4885 |
| US-20170107259-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH ANTIMICROBIAL ACTIVITY | POLL, POLM, POLR1C | OTC 1971/4885DDAH1 582/4885GLP1R 233/4885 |
| US-10730912-B2 | Template-fixed peptidomimetics with antimicrobial activity | POLL, POLM, POLR1C | OTC 2000/4885DDAH1 583/4885GLP1R 226/4885 |
| US-10562933-B2 | Template-fixed beta-hairpin peptidomimetics with protease inhibitory activity | CTSG, CTRL, PREP | OTC 4023/4885DDAH1 932/4885GLP1R 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.