Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 5/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | CTH | P32929 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.52 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.52 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28020711 | 1.00 | MAPT (0.66) | MAPTGAAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL19434711 | 0.84 | L3MBTL1 (0.58) | MAPTGAAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL19434707 | 0.84 | L3MBTL1 (0.58) | MAPTGAAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL17560761 | 0.80 | KMT2A (0.69) | MAPTGAAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL17560759 | 0.80 | KMT2A (0.69) | MAPTGAAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL17560916 | 0.76 | LMNA (0.66) | MAPTGAAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL17560913 | 0.76 | LMNA (0.66) | MAPTGAAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL19434681 | 0.76 | MAPT (0.56) | MAPTGAAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL19434684 | 0.76 | MAPT (0.56) | MAPTGAAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL17561007 | 0.76 | DDX3X (0.68) | MAPTGAAALDH1A1CTHCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170314007-A1 | MEDICAMENT DESIGN POCKET OF ORNITHINE DECARBOXYLASE AND APPLICATION OF MEDICAMENT DESIGN POCKET | CHINA THREE GORGES UNIVERSITY (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20170314007-A1 | MEDICAMENT DESIGN POCKET OF ORNITHINE DECARBOXYLASE AND APPLICATION OF MEDICAMENT DESIGN POCKET | CHINA THREE GORGES UNIVERSITY (CN) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170314007-A1 | MEDICAMENT DESIGN POCKET OF ORNITHINE DECARBOXYLASE AND APPLICATION OF MEDICAMENT DESIGN POCKET | ODC1, PLPBP, OTC | MAPT 3741/4885GAA 3624/4885L3MBTL1 2584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.