Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28777 | 0.85 | MLYCD (0.54) | HPGDALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL11486845 | 0.84 | SMN1; SMN2 (0.85) | SMN1; SMN2HPGDALDH1A1NPC1POLB | |
| Hydrochloric Acid SCHEMBL7476159 | 0.83 | MLYCD (0.53) | HPGDALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL9878124 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2HPGDALDH1A1NPC1POLB | |
| SCHEMBL3303829 | 0.82 | HPGD (0.56) | HPGDALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL4449884 | 0.82 | MAPT (0.56) | SMN1; SMN2HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL286256 | 0.82 | CES2 (0.57) | SMN1; SMN2HPGDALDH1A1PARP10HSD17B1 | |
| SCHEMBL1034311 | 0.80 | MAOB (0.63) | MEN1KMT2APARP10SRD5A2 | |
| SCHEMBL22531823 | 0.80 | MLYCD (0.57) | SMN1; SMN2HPGDALDH1A1NPC1POLB | |
| SCHEMBL8569451 | 0.77 | KDM4E (0.49) | ALDH1A1POLBRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751882-B | Synthesis method of benzofuran | 南京工业大学 | 2024-02-23 | — | — | CN | disclosed |
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |
| CN-114751882-A | Synthetic method of benzofuran | 南京工业大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-111630044-A | Oximino-tetrazole derivatives and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2020-09-04 | — | — | CN | disclosed |
| WO-2020133123-A1 | OXIME-TETRAZOLE DERIVATIVE AND APPLICATION THEREOF IN AGRICULTURE | 东莞市东阳光农药研发有限公司 | 2020-07-02 | — | — | WO | disclosed |
| US-10662174-B2 | BTK inhibitor | HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. (CN) | 2020-05-26 | — | — | US | disclosed |
| EP-3246317-A1 | BTK INHIBITOR | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. (CN) | 2017-11-22 | — | — | EP | disclosed |
| US-20170313683-A1 | BTK INHIBITOR | HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20170313683-A1 | BTK INHIBITOR | HUBEI BIO-PHARMACEUTICAL INDUSTRIAL TECHNOLOGICAL INSTITUTE, INC. (CN) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662174-B2 | BTK inhibitor | BTK, SYK, LYN | SMN1; SMN2 4321/4885HPGD 4511/4885ALDH1A1 4122/4885 |
| US-20170313683-A1 | BTK INHIBITOR | BTK, SYK, LYN | SMN1; SMN2 4321/4885HPGD 4511/4885ALDH1A1 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.