Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5071871 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL16023576 | 0.75 | ALDH1A1 (0.57) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL31202587 | 0.75 | BRPF1 (0.61) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL16009898 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL9871331 | 0.74 | ALDH1A1 (0.56) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL24513132 | 0.72 | BRPF1 (0.36) | ALDH1A1HSD17B10HPGDLMNATSHR | |
| SCHEMBL17680565 | 0.72 | MAOA (0.59) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL11688871 | 0.72 | KDM4E (0.54) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL4774449 | 0.72 | L3MBTL1 (0.58) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD | |
| SCHEMBL19531646 | 0.72 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170312292-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | WUXI APPTEC (SHANGHAI) CO. LTD (CN) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170312292-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | EP300, CREBBP, HDAC1 | ALDH1A1 1533/4885KDM4E 387/4885HSD17B10 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.